After a solid start by opener Dwayne Smith (44) and a valuable 33 off 14 balls by skipper Rohit Sharma in the middle, Glenn Maxwell's 14-ball 37 cameo in the end took the IPL champions past 200-run mark.
This is the highest total for the Mumbai Indians, who scored 142 runs in their last 10 overs today, in the Champions League Twenty20.
It was a team effort with Maxwell adding 41 runs for the sixth wicket with Dinesh Kartik (15 not out) in 2.2 overs towards the fag end.
Put in to bat by Rajasthan Royals, the in-form opener Smith gave Mumbai Indians a perfect start, hitting a six over deep mid-wicket in the third ball of the very first over to set the tone.
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The other opener, Tendulkar, who is playing his final Twenty20 match, took an over to get settled down before he opened up. He started off with a four in James Faulkner's over, a perfectly timed cover drive.
The 40-year-old right handed batsman then followed it up with two successive boundaries in the first two deliveries off Shane Watson's over before the ball crashed into his off-stump to cut short his innings that saw him score a 13-ball 15, including three hits to the fence.
Tendulkar's departure slowed down the rhythm a bit with Ambati Rayudu adopting a cautious approach, relying mostly on singles and twos. Despite that Mumbai Indians managed to bring up their fifty in 6.5 overs, maintaining a decent run rate.