"As long as we're diligent and strive for excellence, there is nothing wrong in using nuclear technology for peaceful energy," Murthy said while speaking at St Xavier's College here.
Citing detractors who quote disasters like Fukushima and Chernobyl, Murthy said the number of people affected in these tragedies are far less than those who die in car accidents.
There is nothing which is risk-free and hence, it is important to look at the trade-offs which are on the table, he said, adding a developed country like France draws 85 per cent of its power from nuclear sources.
Drawing attention to the environmental concerns, he said a nuclear plant generates far less carbon than a thermal power station.
Murthy's comments come at a time of continuing opposition to nuclear plants like Kudankulam, which is operational, and the proposed Jaitapur nuclear project in Konkan region of the Maharashtra.