Musharraf will fly from Dubai to Karachi where his supporters are planning to give him a rousing welcome.
The 69-year-old ex-dictator says he is prepared to risk any danger to stand for election on May 11.
"I am going home as announced. I am not scared of anything - be it the death threat from terrorists or the arrest on arrival," Musharraf said in Dubai after addressing his party supporters at a reception yesterday.
"I am happy I am going back," Gulf News quoted Musharraf as saying.
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Musharraf after arriving at Quaid-e-Azam International airport in Karachi would address a press conference since the authorities have cancelled the NOC for planned holding of All Pakistan Muslim League (APML) rally near the mausoleum of the Quaid-e-Azam for security reasons.
Clearing the way for his homecoming, three Pakistani courts on Friday granted him pre-arrest bail in several cases, including the Akbar Bugti and Benazir Bhutto murder cases, in which he has been declared a proclaimed offender.
Musharraf seized power in a bloodless coup as army chief of staff in 1999 and left the country after stepping down in August 2008.
Since he went into self-exile in early 2009, Musharraf has several times announced his intention to return home.
Last year he delayed a planned homecoming after being threatened with arrest.
Political and security analysts believe that Musharraf's return has only been made possible after some "deals" in which some foreign governments and the military would have played an influential role.