The 37-year-old actress said her mother also asks for her help in getting a hang of Twitter, reported Daily Mirror.
"My mum texts me the most bizarre questions like, 'What should I tweet? Should I get new head shots? Should I take acting classes?," Witherspoon said.
"And I'm like, 'Mom you're a pediatric nurse. It's weird," she added.
The 'Legally Blonde' star, won the best actress Oscar in 2006 for the Johnny Cash biopic 'Walk the Line'.