The "Scream" star praised his wife and said she doing good, reported People magazine.
"She's doing good. It's not easy, it's so hard. I think the second pregnancy is a little harder than the first. She's got morning sickness on this one.
"Being pregnant and watching a little one that's firmly in his terrible twos is pretty difficult. She a trooper, she's doing great. She's my hero," Arquette, 45, said.