"If you ask me I am optimistic at this moment that we will have the series but given the history of Indo-Pak relations one can't say for certain what will be the situation in a few weeks or months," Sethi said on a television channel.
Sethi was the chairman of the PCB when the Big Three formula of governance was adopted by the International Cricket Council and it also led to India and Pakistan signing a 'Memorandum of Understanding' to resume bilateral series which have remained suspended since 2008 after the Mumbai terror attacks.
"The foreign secretaries agreed that cricket was one important way of keeping the channel open for talks and improving relations. That is why I am optimistic that the governments of Nawaz Sharif and Narendra Modi also want the cricket series to take place," he added.
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Pakistan will host India in December as part of the six series MoU which is applicable until 2022 under the new future tours program system of the ICC.
PCB chairman Shaharyar Khan himself has twice visited India in recent times and met with BCCI and key government officials in a bid to convince the governments to clear the series.
"Yes verbally and informally these thoughts were conveyed to the PCB but eventually it was my decision to not become the ICC president and instead nominate our former captain Zaheer Abbas for this honour," he stated.
"Zaheer Abbas, Majid Khan and Javed Miandad were the candidates for nomination to the ICC president's post.