Carlo Saitto, an official at Sant'Eugenio hospital in Rome, told Italian state TV that Daniele died yesterday night after arriving with grave cardiac and respiratory problems.
Daniele had a history of heart trouble.
Daniele was so identified with Naples that its mayor ordered flags flown at half-staff. Yet his style was also in constant evolution, as he experimented endlessly with blues and jazz.
His voice, sexy, bordering on hoarse, alternately soaring or soft, was a distinctive vehicle for songs that often mixed the Neapolitan dialect with Italian and even English.
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In his 1980 hit album "Nero a meta'" (Half-black), Daniele blended American blues sounds with popular Neapolitan songs. Folding jazz into his work, he performed with stars including Wayne Shorter and Chick Corea.
Like his chaotic, port city hometown, Daniele absorbed countless influences.
He composed the lyrics and music, including the hit "Quando" (When), for three movies of the late Neapolitan actor-director-comic, Massimo Troisi.
Born on March 19, 1955, Giuseppe "Pino" Daniele grew up in a city celebrated for song. His own first song was entitled "Terra Mia" (My Land).