The Cassini spacecraft made its closest approach to Titan today at an altitude of 119,049 kilometres above the moon's surface.
Images and other science data taken during the encounter are expected to begin streaming to Earth soon.
Navigators will analyse the spacecraft's trajectory following this downlink to confirm that Cassini is precisely on course to dive into Saturn at the planned time, location and altitude.
The geometry of the flyby causes Cassini to slow down slightly in its orbit around Saturn.
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This lowers the altitude of its flight over the planet so that the spacecraft goes too deep into Saturn's atmosphere to survive, because friction with the atmosphere will cause Cassini to burn up.
Cassini has made hundreds of passes over Titan during its 13-year tour of the Saturn system - including 127 precisely targeted encounters - some at close range and some, like this one, more distant.
"This final encounter is something of a bittersweet goodbye, but as it has done throughout the mission, Titan's gravity is once again sending Cassini where we need it to go," said Maize.
Cassini is ending its tour of the Saturn system with an intentional plunge into the planet to ensure Saturn's moons - in particular Enceladus, with its subsurface ocean and signs of hydrothermal activity - remain pristine for future exploration.
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