Silica is a rock-forming compound containing silicon and oxygen, commonly found on Earth as quartz.
The area the rover is investigating lies just downhill from a geological contact zone the rover has been studying near "Marias Pass" on lower Mount Sharp.
The Curiosity team decided to back up the rover 46 metres from the geological contact zone to investigate the high-silica target dubbed "Elk."
The decision was made after they analysed data from two instruments, the laser-firing Chemistry & Camera (ChemCam) and Dynamic Albedo of Neutrons (DAN), which showed elevated amounts of silicon and hydrogen, respectively.
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"One never knows what to expect on Mars, but the Elk target was interesting enough to go back and investigate," said Roger Wiens, the principal investigator of the ChemCam instrument from the Los Alamos National Laboratory in New Mexico.
ChemCam is coming up on its 1,000th target, having already fired its laser more than 260,000 times since Curiosity landed on Mars on August 6, 2012.
Before Curiosity began further investigating the high-silica area, it was busy scrutinising the geological contact zone near Marias Pass, where a pale mudstone meets darker sandstone.
MAHLI is short for Mars Hand Lens Imager.
The rover had reached this area after a steep climb up a 6-metre hill. Near the top of the climb, the ChemCam instrument fired its laser at the target Elk, and took a spectral reading of its composition.