This target, called "Mojave," displays copious slender features, slightly smaller than grains of rice, that appear to be mineral crystals.
A chance to learn their composition prompted the Curiosity science team to choose Mojave as the next rock-drilling target for the 29-month-old mission investigating Mars' Gale Crater.
This week, Curiosity is beginning a "mini-drill" test to assess the rock's suitability for deeper drilling, which collects a sample for onboard laboratory analysis.
The Mojave drilling begins Curiosity's third round of investigating the basal layer of Mount Sharp exposed at an area called "Pahrump Hills."
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In the first round, the rover drove about 110 metres and scouted sites ranging about 9 metres in elevation. Then it followed a similar path, investigating selected sites in more detail.
That second pass included inspection of Mojave in November 2014 with the dust-removal brush, close-up camera and Alpha Particle X-Ray Spectrometer on the rover's arm.
"The crystal shapes are apparent in the earlier images of Mojave, but we don't know what they represent," said Curiosity Project Scientist Ashwin Vasavada at NASA's Jet Propulsion Laboratory, Pasadena, California.
"We're hoping that mineral identifications we get from the rover's laboratory will shed more light than we got from just the images and bulk chemistry," said Vasavada.
Curiosity's Chemistry and Mineralogy instrument, or CheMin, can identify specific minerals in rock powder from a drilled sample.
"Are they salt crystals left from a drying lake? Or are they more pervasive through the rock, formed by fluids moving through the rock? In either case, a later fluid may have removed or replaced the original minerals with something else," Vasavada added.