"If India has to produce good scientists, quality science has to be promoted," Rao, who is Chairman of Scientific Advisory Council to the Prime Minister, said.
He was delivering a lecture on 'Doing Science in India' at Post Graduate Institute of Medical Education and Research (PGIMER) here.
"To promote science in India, young and talented people have to be encouraged by good teachers because science is about ordinary people doing extraordinary things. Real science is done in small labs by crazy individuals," he said.
Rao said a scientist has to be motivated by the values of humanity, generosity and tradition as these feed the quality of his work.
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He further said that to persist with science, a scientist cannot afford to be angry particularly in India and has to face his critics with a sense of humour.
"A scientist has to be mad about his work and deal with a judgmental society. Personal satisfaction and enjoyment help achieve the goal," he said.
"We have a large number of bright and sharp students in institutions like the PGI and IITs but they need to work for science in India selflessly," he said.
Stating that media could play a huge role in promoting science in the country, Rao said media should highlight events and news related to science which is not being adequately done at present.