"The condition of former president Nelson Mandela, who is still in hospital in Pretoria, has become critical," said presidential spokesman Mac Maharaj, 16 days after Mandela was admitted to the Mediclinic Heart Hospital for treatment of the lung infection.
President Jacob Zuma, accompanied by African National Congress Deputy President Cyril Ramaphosa, visited Mandela last evening.
"They were briefed by the medical team who informed them that the former President's condition had become critical over the past 24 hours," a statement from the Presidency said.
Zuma and Ramaphosa also met Mandela's wife Graca Machel at the hospital and discussed his health condition.
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"The doctors are doing everything possible to get his condition to improve and are ensuring that Madiba (Mandela's clan name) is well-looked after and is comfortable. He is in good hands," Zuma was quoted as saying in the statement.
The latest statement from the Presidency is the strongest indication yet that all is not well with the ailing elder statesman, who will turn 95 in three weeks' time.
"The President and Mr Ramaphosa were assured by the doctors that when the ambulance transporting former President Mandela to hospital on the 8th of June developed engine problems, all care was taken to ensure that his medical condition was not compromised," the Presidency said, in a bid to assuage the people's concerns.