A triangular contest is expected during the 13th national convention starting tomorrow for the top post in the party which lost power last year to a largely-leftist coalition under an arrangement between major parties to elect a new government after the promulgation of the Constitution.
But three-time prime minister Sher Bahadur Deuba, who comes from the same social democratic tradition as Koirala, is seen as the frontrunner to take over the party which has had traditionally close ties with India, media reports said.
The four-day meet has been convened just three weeks after the death of Koirala, a moderate figure in the country's troubled politics, who died of pneumonia on February 9.
Koirala had a balanced view about India and his death presented a succession problem for the Koirala dynasty.
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The party will also elect new central executive committee and present its political document during the convention.
(Reopens FGN 27)
The convention begins with a public meeting and top party leaders addressing the meeting, followed by a closed session on Friday. During that session, party's central committee will present policy and programmes, general secretary's report as well as financial report will be presented.
The convention is likely to amend the party statute to reform its structure and make the party more inclusive and democratic. Various foreign leaders have been invited for the inugural ceremony.
Nepal has been in turmoil since the new constitution was adopted in September. The Madhesi community, which has close ties to India launched protests against the charter, saying it did not address their demand for a greater say in government.
The popular Nepali Congress has some 600,000 members. It led the Peoples Movement of 2006 that after years of conflict abolished the 239-year-old monarchy.
However, NC pursues the ideology of democratic socialism and is known for its centrist policies.