Researchers have long known of the phenomenon of infantile amnesia. This refers to the absence of long-term memory of events occurring within the first 2-3 years of life, and little long-term memories for events occurring until about 7 years of age.
Studies have shown that though young children can remember events in the short term, these memories do not persist.
The new study by Drs Paul Frankland and Sheena Josselyn, from the Hospital for Sick Children in Toronto, shows that this amnesia is associated with high levels of new neuron production - a process called neurogenesis - in the hippocampus, and that more permanent memory formation is associated with a reduction in neurogenesis.
In older mice they stimulated increased neurogenesis (thereby replicating the conditions normally seen in younger mice).
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Frankland was able to show a causal relationship between a reduction in neurogenesis and increased remembering, and the converse, decreased remembering when neurogenesis increased.
"Why infantile amnesia exists has long been a mystery. We think our new studies begin to explain why we have no memories from our earliest years," Frankland said.