The former "Party of Five" and "Scream" star joins Kevin Spacey and Robin Wright as a series regular for the upcoming fourth season of the Netflix hit drama.
Her role, however, is still kept under wraps, reported Ace Showbiz.
Besides known for her roles on drama series "Party of Five" and "Scream" movie series, Campbell starred in "Wild Things", "Panic" and "The Company".
She also guest starred on "Grey's Anatomy" and "Mad Men", will next appear on "Welcome to Sweden" season 2.
"House of Cards" was renewed for a fourth season in April and will return with new episodes sometime in 2016. It was recently reported that the show would feature a younger couple to rival Frank (Spacey) and Claire (Wright).