Officials in Ukraine reported serious intrusions of the country's power grid as well as at banks and government offices, where one senior executive posted a photo of a darkened computer screen and the words, "the whole network is down." The prime minister cautioned that the country's "vital systems" hadn't been affected.
Russia's Rosneft oil company also reported falling victim to hacking and said it had narrowly avoided major damage, as did Danish shipping giant AP Moller-Maersk.
The attack was confirmed to have spread beyond Europe when US drugmaker Merck, based in New Jersey, said its systems had also been compromised.
The number of companies and agencies reportedly affected by the ransomware campaign was piling up fast, and the electronic rampage appeared to be rapidly snowballing into a worldwide crisis.
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There's very little information about what might be behind the disruption at each specific company, but cybersecurity experts rapidly zeroed in on a form of ransomware, the name given to programs that hold data hostage by scrambling it until a payment is made.
Some analysts were calling the new form of ransomware Petya.
It's not clear whether or why the ransomware has suddenly become so much more potent, but Botezatu said that it was likely spreading automatically across a network, without the need for human interaction.
Such self-spreading software, often called "worms," are particularly feared because they can replicate rapidly, like a contagious disease.
The world is still recovering from a previous outbreak of ransomware, called WannaCry or WannaCrypt, which spread rapidly using digital break-in tools originally created by the US National Security Agency and recently leaked to the web.
"Data breaches and cyber hacks are one of the biggest risks facing business worldwide," said Michelle Crorie, a partner at law firm Clyde & Co. Who specializes in cybersecurity issues.
"The WannaCry attack and now Petya clearly demonstrate that hackers do not discriminate which type of business they are targeting."