The research improves the prospects of developing computing and communication technologies based on quantum properties of light and matter.
The atomically thin semiconductors consisted of two-dimensional (2D) layer of molybdenum and sulfur atoms arranged similar to graphene.
Researchers from City College of New York led by Dr Vinod Menon sandwiched the 2D material in a light trapping structure to realise the composite quantum particles.
"Besides being a fundamental breakthrough, this opens up the possibility of making devices which take the benefits of both light and matter," said Menon.
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"What is so remarkable and exciting in the work by Vinod and his team is how readily this strong coupling regime could actually be achieved," said Dr Dirk Englund, a professor at MIT whose research focuses on quantum technologies based on semiconductor and optical systems, and who was not involved in the study.
"They have shown convincingly that by coupling a rather standard dielectric cavity to exciton-polaritons in a monolayer of molybdenum disulphide, they could actually reach this strong coupling regime with a very large binding strength," he said.
The study appears in the journal Nature Photonics.