Notices were issued to the Chief Secretary, UP Government and the District Magistrate, Lakhimpur calling for reports within two weeks, an NHRC statement said.
They have also been asked to inform what relief has been given or proposed to be given to the affected persons.
The Commission took suo motu cognisance of media reports which alleged complicity of Forest Department officials in a fire that broke out in Dilwar Nagar settlement in Lakhimpur district in which at least 300 huts were destroyed on June 6.
The Commission has observed that the contents of the media reports, if true, raise a serious issue of violation of right to life and shelter of the victims.