However, FMCG and IT segments witnessed some buying interest at lower levels.
Overseas, European stocks were trading lower following declines overnight on Wall Street as the closeness of the US elections continues to rattle nerves in the market.
Most Asian stocks declined as investors were spooked by growing uncertainty about the outcome of the US Presidential election next week.
It saw an intra-day movement of about 103.75 points.
Also Read
On the sectoral front, Pharma fell (4.66 per cent) followed by Realty (3.82 per cent), Metals (3.31 per cent), Infra (1.41 per cent), PSU Bank (1.49 percent), Energy (0.96 percent), Finance Service (0.89 pct) and Auto (0.78 per cent).
However, FMCG and IT rose by 1.87 and 1.17 per cent, respectively.
The index laggards were Sun Pharma (7.41 per cent), Dr Reddy (5.60 per cent), InfraTel (4.42 per cent), Aurobindo Pharma (5.36 per cent), Coal India (3.39 per cent), HeroMotoco (2.93 per cent), Lupin (2.95 per cent).
A total of 1,436 scrips declined, 223 advanced while 40 remained unchanged. Total securities that hit their price bands were 139.
Turnover in the cash segment rose to Rs 23,946.66 crore, from Rs 19,600.49 crore as on Thursday.
A total of 11,004.38 lakh shares changed hands in 92,02,071 trades. The market capitalisation of NSE stood at Rs 1,07,77,140.28 crore.
Disclaimer: No Business Standard Journalist was involved in creation of this content