A falling rupee, which has breached the 61-level against the US dollar, also had a negative impact on the stock market.
Speculation is rife that the US central bank may hike interest rates during its two-day meeting on September 16-17 following improvement in the world's largest economy. Such a move will affect liquidity from the market, mainly emerging ones, as foreign funds will prefer to invest in the US.
Oil market companies (OMCs), too, suffered losses on expectations of a cut in petrol and diesel prices next week.
The market shrugged off positive cues like a fall in crude oil prices below USD 99 a barrel mark and sustained capital inflows.
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The 50-share bellwether index moved in negative terrain throughout the day before closing at 8,094.10, down 58.85 points, or 0.72 per cent, over the last close.
Top five losers from Nifty were Cairn India 2.66%, Hero Moto 2.43%, BPCL 2.27%, ITC 2% and Infosys 1.84%. Notable gainers were IDFC 2.08%, DLF 1.64%, ICICI Bank 1.58%, Power Grid 1.57% and Sesa Sterlite 1.56%.