The market rode between gains and losses during morning trade on the back of mixed Asian cues ahead of tomorrow's crucial Brexit poll which decides Britain's fate in the European Union.
However, good buying interest was seen in pharma counters, while midcap and smallcap shares witnessed profit booking.
Elsewhere, Asian stocks ended mixed as investors were guardedly optimistic about a 'Remain' vote in the referendum.
Meanwhile, foreign portfolio investors bought shares worth net Rs 484.66 crore yesterday, as per provisional data.
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The 50-share index resumed lower at 8,213.65 and hovered between 8,238.35 and 8,153.25 before ending at 8,203.70, showing a loss of 16.20 points or 0.20 per cent.
Major losers were Tata Motors DVR (3.05 per cent), Bharti Infratel (2.59 per cent), Tata Motors (2.52 per cent), GAIL (2.03 per cent) and UltraTech Cement (1.38 per cent).
Notable gainers were Adani Ports (2.02 per cent), Dr Reddy's Lab (1.84 per cent), Coal India (1.44 per cent), Ambuja Cement (1.10 per cent) and Lupin (0.85 per cent).
Turnover in cash segment declined to Rs 15,113.82 crore from Rs 15,139.13 crore yesterday. A total of 9,190.59 lakh shares changed hands in 68,59,870 trades.
The market capitalisation of NSE stood at Rs 99,24,483 crore.