However, pharma, PSU bank and energy counters firmed up on robust buying.
Asian shares hit a 10-year peak cheered by record highs on Wall Street following Apple's new launches and as North Korea fears eased. Europe's main markets all dipped in early trade.
The Nifty opened higher at 10,099.25 and moved in a range of 10,131.95 and 10,063.15 before ending at 10,079.30, a modest loss of 13.75 points, or 0.14 per cent.
It saw an intra-day movement of about 68.80 points.
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Gainers included Pharma 1.61 per cent, PSU Bank 0.35 per cent, Energy 0.24 per cent and Bank 0.19 per cent.
Major index losers were BPCL, IOC, ITC, Indiabulls Housing Finance and Eicher Motors.
Index gainers included Tata Powers, Sun Pharma, Reliance, Dr Reddy's and Bank Of Baroda.
Market breadth, indicating the overall health of the market, was tilted towards the negative end. A total of 1,081 scrips declined, 603 advanced while 76 remained unchanged.
Total securities that hit their price bands were 129.
A total of 15,704.81 lakh shares changed hands in 9,769,959 trades. The market capitalisation of listed firms on the NSE stood at Rs 1,33,77,616 crore.
Disclaimer: No Business Standard Journalist was involved in creation of this content