Investors stayed on the sidelines ahead of the release of December quarter GDP growth data tomorrow.
Overseas, most European shares were trading higher, while Asian shares reversed early gains and ended lower ahead of US Federal Reserve Chairman Jerome Powell's highly-anticipated testimony later in the day.
The Nifty 50 index fell 28.30 points or 0.27 percent to close at 10,554.30 after moving in a range of 10,631.65 and 10,537.25. It saw an intra-day movement of about 94.40 points.
On the other hand, Energy rose 0.59 per cent, FMCG 0.31 per cent and IT 0.26 per cent.
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Major index gainers included Dr Reddy's, Bharti Airtel, NTPC, Hero MotoCo, RIL, NTPC, HUL and Infosys.
The losers were Ambuja Cement, Axis Bank, SBI, Sun Pharma, Coal India, Zee, Bajaj Finance and GAIL.
The market breadth, indicating its overall health, turned negative. A total of 620 scrips advanced, 1,177 declined, while 57 remained unchanged.
Turnover in the cash segment fell to Rs 28,193.66 crore from Rs 29,176.42 crore as on Monday.
A total of 14,039.50 lakh shares changed hands in 97,85,459 trades. The market capitalisation of listed firms on the NSE stood at Rs 1,46,13,418.55 crore.
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