Ravi Venkatesan also resigned as co-chairman, but will continue as an independent director.
Vishal Sikka, who quit last week as CEO but was made vice-chairman till his successor was appointed, also quit the board with immediate effect, the company said in a statement after its board meeting.
The board shake-up meets a key demand of the founder group led by N R Narayana Murthy, who had demanded a clean-up at the country's second largest software services firm.
The crisis had been brewing at Infosys since Sikka abruptly resigned last week, blaming founders for slander.
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