"It (Jaitapur power plant) is now at a stage where one cannot go back," Fadnavis told PTI in an interview.
The project was among the 17 pacts signed between the two countries during Prime Minister Narendra Modi's recent visit to France.
The Jaitapur project in Maharashtra's Ratnagiri district, where French company Areva is to set up six nuclear reactors with total power generation capacity of about 10,000 MW, is stuck for long following protests and differences over the cost of electricity to be generated.
"The Shiv Sena has long been opposing the Jaitapur nuclear project. The BJP feels that India requires nuclear power and when the PM does something, he does it for the country's benefit. This project will be completed at any cost now," he said.
According to Shiv Sena, the energy produced from the project will be beneficial for the whole country, but Maharashtra would be at the maximum risk.