The team from Northwest A&F University and the National Beef Cattle Improvement Centre in Yangling, Shaanxi province, successfully introduced a gene into foetal cells from Luxi Yellow cattle, a Chinese breed with a high beef yield.
The fat1 gene, isolated from a nematode worm, codes for desaturase enzymes that are involved in the conversion of n-6 to n-3 polyunsaturated fatty acids.
A diet rich in long chain n-3 polyunsaturated fatty acids, also known as omega-3 oils, can help protect against cardiovascular diseases, obesity and neurodegenerative diseases.
Introducing the fat1 gene to cattle increased the levels of beneficial oils by over five times.
Also Read
"We have provided the first evidence that it is possible to create a new breed of cattle with higher nutritional value in terms of their fatty acid composition," said corresponding author Linsen Zan from the College of Animal Science and Technology at the university.
Of 14 calves that successfully received the fat1 gene, 11 died at less than four months old, mainly from inflammation and from an infection common to cattle, haemorrhagic septicaemia.
A similar strategy could be used for cattle - producing feedstock rich in omega-3s - but the new study shows that elevated levels can be directly produced in beef, researchers said.
Similar genes have previously been introduced to pigs, dairy cattle and sheep by international research groups.
The study is published in Springer's journal Biotechnology Letters.