Senior medical experts have been rushed to the hospital to examine Shukla's condition, jail Superintendent Viresh Raj Sharma told PTI adding he was feeling uneasy in his barrack and was shifted from there last night.
A special CBI court had on May 17 remanded Shukla to judicial custody for 14 days.
Special CBI judge A K Singh remanded the IAS officer in judicial custody, rejecting the CBI's plea for three more days of his custody for further interrogation.
Singh had fixed May 28 as the next date of hearing.
Shukla was arrested on May 10 by the CBI for alleged bungling in upgradation of 89 district hospitals under NRHM programme causing a loss of nearly Rs 22.5 crore to the exchequer.
He was held from Lucknow airport while he was going to Delhi for some treatment.