The conversation will be followed by a screening of DiCaprio's new climate documentary "Before the Flood", according to The Hollywood Reporter.
At the inaugural South by South Lawn: A White House Festival of ideas, art, and action, the commander-in-chief and the 41-year-old star will take part in a conversion with climate scientist Dr Katharine Hayhoe about the importance of protecting the planet for future generations.
"The Revenant" star expressed his excitement for the upcoming event by tweeting, "Looking forward to sitting down with @POTUS and @KHayhoe for a discussion on #climatechange.