Obama said if Russian leaders thought they could drive a wedge between Europe and the United States "they clearly miscalculated."
Obama spoke during a news conference at the Council of the European Union, after a working lunch with European Council President Herman Van Rompuy and European Commission President Jose Manuel Barroso that participants said was dominated by discussion of Ukraine. Van Rompuy called Russia's action in Crimea "a disgrace in the 21st century, and we will not recognize it."
Obama said some countries have legitimate questions about whether free trade deals will benefit them in the long-term. But he cautioned skeptics to wait to see what's negotiated before reaching conclusions.
The president said some suspicions about the so-called TTIP have been unjustified. He declared that he has fought for consumer and environmental protections during his political career and will not sign legislation that would weaken those protections.
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Obama's own relations with Europe have been hurt by revelations of communications prying by the US National Security Agency. Van Rompuy said EU leaders conveyed their concerns directly to Obama in their meeting, and the president agreed to take aggressive steps to address the issue. Van Rompuy called for "equal treatment of EU and US citizens."
Obama said he wants to see every NATO partner "chip in" for mutual defense and that members should examine their defence plans to make sure they reflect current threats.