The administration will submit the request "shortly," the White House said in a statement that did not specify a timeframe.
"The requested resources will build on our ongoing preparedness efforts and will support essential strategies to combat this virus," the White House said in a statement.
Zika has been linked to a surge in Latin America of births of children with microcephaly, or abnormally small heads and brains.
The hardest hit country is Brazil, which hosts the Summer Olympics starting in August.
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Some countries are taking the extraordinary step of urging women to put off having children for now, as it is believed the virus is passed on from infected pregnant women to their fetuses.
The continental United States has yet to see cases of transmission of the virus, which is carried by a mosquito.
But Puerto Rico and other US territories in warmer areas with that kind of mosquito are looking for evidence of transmission, the US statement said.
US authorities report 50 laboratory-confirmed cases among US travelers from December of last year to February 5.
"As spring and summer approach, bringing with them larger and more active mosquito populations, we must be fully prepared to mitigate and quickly address local transmission within the continental US, particularly in the southern United States," the statement said.