"The Prime Minister's visit will highlight the fundamental importance of the US-UK relationship - through which together we address a broad range of shared global and regional security concerns," the White House said of Obama's meeting with Cameron later today.
After the meeting the two leaders are scheduled to address a joint news conference at the Rose Garden of the White House.
"As is always the case, when the President meets with Prime Minister Cameron, they will speak about a range of subjects. The relationship between our two nations is extraordinarily close, and we work and cooperate on matters across the international spectrum," White House Press Secretary Jay Carney told reporters.
Ahead of the Cameron's visit, Downing Street said, "ending the bloody and brutal conflict in Syria" along with the upcoming G-8 Summit would be on top of his agenda in his (Cameron's) meeting with Obama.
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Obama-Cameroon meeting also comes ahead of the US President's visit to Britain and Germany next month.
Obama will attend the G-8 Summit at Lough Erne, Northern Ireland, hosted by Cameron, from June 17-18.
"The Summit and related meetings will provide the President and his fellow world leaders an opportunity to address pressing economic, political, and security challenges around the globe and to promote the advancement of trade and greater transparency among G-8 members and the developing world," Carney said.