Overweight children naturally produce higher levels of a key stress hormone than other youngsters, researchers said.
The body produces the hormone cortisol when a person experiences stress, researchers said.
When a person faces frequent stress, cortisol and other stress hormones build up in the blood and, over time, can cause serious health problems.
Researchers measured cortisol in scalp hair, which reflects long-term exposure and has been proposed to be a bio-marker for stress. The study is the first to show obese children have chronically elevated levels of cortisol.
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"By analysing children's scalp hair, we were able to confirm high cortisol levels persisted over time," said van den Akker.
The observational case-control study analysed hair samples from 20 obese children and 20 normal weight children to measure long-term cortisol levels. Each group included 15 girls and 5 boys between the ages of 8 and 12.
Obese subjects had an average cortisol concentration of 25 pg/mg in their scalp hair, compared to an average concentration of 17 pg/mg in the normal weight group.
"Because this study took an observational approach, more research will determine the cause of this phenomenon," van den Akker said.
"We do not know whether obese children actually experience more psychological stress or if their bodies handle stress hormones differently. Answering these key questions will improve our understanding of childhood obesity and may change the way we treat it," said van den Akker.
The study was published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism.