Spencer will play Johanna, the leader of Amity, which is the faction in the dystopian society that is said to be dedicated to peace and trust.
She will star alongside Woodley, Theo James and Kate Winslet. The film will be directed by Robert Schwentke from a screenplay by Brian Duffield and Akiva Goldsman, reported Variety.
'Insurgent' will be released on March 20. The third book, 'Allegiant' will be split into two films that are slated for release on March 18, 2016, and March 24, 2017, respectively.
Spencer won a best supporting Oscar for her role in 'The Help'.