Temperatures were forecast to hover above 40C (104F) over the next four days but tournament officials said plans were in place to look after the players in the sweltering conditions.
"Tennis, as a sport, is relatively low risk for major heat problems compared to football and continuous running events," the tournament's chief medical officer Tim Wood said.
"Certainly in the next four days the players will have plenty of chance to acclimatise.
"They might actually get better, particularly with the 48 hours' rest between matches."
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"We have had players almost die from drinking too much. So the danger is overdrinking, not underdrinking and becoming dehydrated," he said.
"Given the length of time tennis matches generally go for and the sweat rate of most normal, healthy athletes, they won't get to a state where they get too critically dehydrated."
"They do get an advice sheet that's sent out to them before the tournament starts on the fact that Melbourne's weather is rather variable," he said.
"We can get 16C to 42C degrees at any time. We give them advice on how best to prepare for playing under those conditions.