Crude prices had already been falling in recent weeks owing to a global supply glut despite forecasts of demand growth.
US benchmark West Texas Intermediate for September delivery fell 83 cents to USD 44.13 a barrel compared with Monday's close.
Brent North Sea crude for September dropped 66 cents to stand at USD 49.75 a barrel in London afternoon deals.
Prices had rebounded yesterday from multi-month low points.
Fawad Razaqzada, analyst at trading group Forex.Com said "concerns about the Chinese economy... (are) continuing to weigh heavily on commodities."
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China's central bank today devalued the yuan by nearly two percent against the US dollar, as authorities seek to push market reforms and bolster the world's second-largest economy.
A cheaper yuan will make Chinese exports less expensive, which could potentially boost their overseas sales.
"Clearly, the market has interpreted the move as a sign that the health of the Chinese economy is probably worse than even what the official data suggests," added Razaqzada.
Despite concerns over China, OPEC today revised upward its forecast for global oil demand growth in 2015 and maintained projected record levels of world consumption next year.
Oil prices collapsed 60 percent between last June and January, hitting a low of USD 45 largely owing to a supply glut caused by the boom in US shale oil.
And despite showing signs of a recovery earlier this year, they have started to once more slip back.
Yesterday meanwhile, the World Bank warned that the lifting of sanctions related to Iran's nuclear programme would have a "significant impact" on the world oil market in 2016.
Elsewhere on commodity markets today, aluminium hit a six-year low point at USD 1,573.50 a tonne on the London Metal Exchange.