This will be in addition to Oman Air's flight service between Muscat and Kozhikode which is the latest destination in the airline's fleet and network expansion programme.
The new direct service will start from March 27 and the three-and-a-half hour flight will depart Salalah at 01.10 hrs and arrive in Kozhikode at 06.20 hrs.
The return flight will leave Kozhikode at 07.00 hrs and arrive in Salalah at 09.15 hrs (local time), the airline said in a statement.
Existing frequencies between Muscat and Kozhikode have also been increased from one daily to twice daily since February this year.
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Oman Air is growing its weekly capacity to India with frequencies increasing on five of the airline's key Indian destinations.
Mumbai, Delhi and Hyderabad increase from twice daily to three times daily.
Kozhikode increases from once daily to three times daily and Lucknow increases from once daily to twice daily.
The growth in capacity follows the revised flight agreement Oman and India in December 2016, when the number of weekly seats was increased to 27,405 seats for both countries, compared to 21,145 seats, an increase of 6,258 seats per week.
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