It was not immediately clear if the crash was an accident or the result of hostile action.
"An International Security Assistance Force service member died as a result of a helicopter crash in southern Afghanistan today," ISAF said.
"Our thoughts and prayers go out to the family and friends affected by this tragic event."
Aircraft crashes have been a regular risk for the ISAF mission in Afghanistan, with troops relying heavily on air transport to battle the Taliban insurgency across the south and east of the country.