The accident took place yesterday morning, at around 8.30 pm, near Saket road junction as the Tata Sumo in which the victims were travelling ran into the trailer from behind.
Julekha Shaikh (15) and Hajira Shaikh (6), the two girls, were seriously injured. Their father Hajimiya Khalil Shaikh escaped unscathed, while Mehboob Ali Mohammed Ali Shaikh (32), the driver, died on the spot.
Police have registered a case of negligence against Mohd Ali Shaikh (28), driver of the trailer.