The band of boys broke down to tears as they visited the poverty-hit city, reported the Mirror online.
A collection of clips of their visit to Accra was shown during the final of the television show 'Let's Dance For Comic Relief'.
One Direction's Harry Styles previously said of the visit to Ghana, "We all had moments. If you get involved in it and you don't cry you're superhuman."
The boys filmed scenes for their charity single, a fusion of Blondie's 'One Way or Another' and The Undertones 'Teenage Kicks', while they were out in Africa.