Despite their overwhelming success in other tournaments, the red-and-gold's best finish has been runners-up in the top-tier league, which is speculated to be merged with ISL from 2017-18.
Trevor Morgan, East Bengal's favourite who has guided the team to Federation Cup titles and I-League runners-up twice, is back in his second stint. The Englishman would be desperate to prove a point.
In the midfield, NorthEast United FC's Rowllin Borges has joined the side after his sparkling show in the ISL. His coordination with Mehtab Hossain will be much-anticipated.
Trinidadian Willis Plaza and Haitian Wedson Anselme have been the two foreign striking options along with Thongkhosiem Haokip, Nikhil Poojary and VP Suhair.
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They have roped in the experienced pro Khalid Jamil, the Kuwait-born former India international, who coached Mumbai FC for seven years.
They will also rely on the experienced Liberian forward Alfred Jaryan, who will be representing the side for a second successive season.
Ivory Coast's Kamo Bayi, who played in Salgaocar in the Goa league following a stint at the George Telegraph in the 2016 Calcutta Football League, and Nigerian defender Eze Kingsley are the other two foreign players.