The opposition called for "unravelling the mystery" behind the death of the AIADMK supremo, who passed away on December 5 last after 75 days of hospitalisation.
Forest Minister Dindigul C Srinivasan, whose comments about the "lies" have drawn flak from the opposition, sought to make light of Stalin's demand by stating "it was not new for him to seek such a probe".
"No one was allowed to meet the late chief minister. Whoever came, would be briefed by Sasikala's relatives that she was all right," he had said.
"We were afraid of Sasikala at that time and lied about Jayalalithaa's health condition," he had claimed.
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As the opposition latched onto his statement, the Tamil Nadu minister said they (AIADMK leaders) conveyed to the outside world whatever was told to them by Sasikala.
Speaking to reporters at his native Dindigul, Srinivasan said, "I do not care even if a CBI inquiry is ordered".
The minister also urged sidelined AIADMK leader and Sasikala's nephew T T V Dhinakaran to release "video proof" of the treatment given to Jayalalithaa as being claimed by him.
The enquiry commission ordered by Chief Minister K Palaniswami in the matter would soon start its probe, and Dhinakaran would have to submit whatever proof he had in his possession on the matter before the commission, he said.
"Since the central government had assisted in the treatment of Jayalalithaa, it has a responsibility to unravel the mystery surrounding her death. Therefore, using its authority, it should immediately order a CBI probe into the matter," he said.
The DMK leader said he was making the plea in his capacity as the Leader of Opposition in the state assembly.
He also questioned the veracity of Jayalalithaa's signature on a statement made in her name during her hospitalisation seeking support for AIADMK candidates in the bypolls to three state Assembly seats last year.
Referring to Srinivasan's admission, Stalin said a "question arises" on how an advice was given by Jayalalithaa to re-allocate the portfolios held by her to then finance minister O Panneerselvam in October last.
Stalin recalled that the ruling AIADMK leaders had criticised his father and DMK president M Karunanidhi when he had demanded the release of pictures of Jayalalithaa undergoing treatment and related details since she was the chief minister.
"The AIADMK party members are now demanding the release of not just photographs, but also videos," he said referring to the face-off between Dhinakaran and the unified AIADMK over the matter.
"Who really took care of the chief minister? Is it just the hospital management.... did the prime minister enquire about her health? Why did not he visit her?" he asked.
A host of personalities including BJP president Amit Shah, Union Finance Minister Arun Jaitley, Congress vice-president Rahul Gandhi and Kerala Chief Minister Pinarayi Vijayan had visited the Apollo Hospitals, where Jayalalithaa was admitted on September 22, 2016.
BJP state unit president Tamilisai Soundarrajan said the people "always had a doubt" over the leader's death and demanded an "honest probe".
"On whose instructions was the security cover provided to her removed during hospitalisation?" he asked.
Ramakrishnan called for a court-monitored probe into the treatment and subsequent death of Jayalalithaa.
The PMK also demanded a probe into her death, especially in the light of Srinivasan's remarks.
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