Lohan, who is more famous for her frequent run-ins with the law, features in the docu-series which follows the former Disney star since she's released from rehab. It will debut in March, reported Ace Showbiz.
In a sneak peek from the show, Winfrey says, "This is exactly what everybody said was going to happen. She doesn't understand. This is her life - you think you have forever."
Winfrey is also shown telling Lohan, "My truth is I really do want you to win...But if that isn't what you want I'm okay with that. I will tell these guys to pack up and leave today."
OWN president Sheri Salata says that Lohan often shuts out the crew.
Lohan herself admits, "I know this is my last shot at doing what I have to do.