Winfrey was recently at the receiving end of her "Color Purple" co-star Rae Dawn, who used racially derogatory terms to describe the media mogul.
"You cannot be my friend and use that word around me. It shows my age, but I feel strongly about. I always think of the millions of people who heard that as their last word as they were hanging from a tree, Winfrey told Parade magazine.
Winfrey, 59, feels youth have no idea what the civil rights movement is all about. She thinks Martin Luther King's dream has not been completely fulfilled.