The aircraft was on a routine night operational training mission when it went down in Gadaap area near Karachi, the Pakistan Air Force (PAF) said in a statement.
The pilot of the aircraft Squadron Leader Tanvir Ahmed was killed in the crash, it said.
No loss of civilian life and property has been reported on ground.
A board of inquiry has been ordered by the PAF to determine the cause of accident.
This is the third incident in recent times that a PAF training aircraft has crashed.