The network announced at Comic-Con International that Brewster will reprise his iconic role as Special Agent Emily Prentiss for multiple episodes, reported Digital Spy.
Prentiss joins forces with her old pals at the FBI's Behavioral Analysis Unit when the safety of untold innocents is threatened by 13 serial killers busting out of jail.
"We're excited to have Paget Brewster back for multiple episodes in our 12th season," executive producer Erica Messer said.
"The BAU can use more help this year since they've got a lot of known and unknown subjects to catch."
"Criminal Minds" returns on September 28.