Police officials said that investigations were being conducted into the incident but initial inquiry had shown no criminal record for the dead man nor was he carrying any ammunition or weapons.
"According to the Rangers they signalled Ghulam Haider to stop his car but he did not, over which the officials opened fire at him, killing him on the spot," one official said.
Haider's car consequently collided with a motorcycle, injuring the rider.
The Rangers have given no official statement as yet on the incident.
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The Rangers performance has also come under fire in the Supreme Court and Sindh High Court during hearings on the law and order situation in Karachi which is Pakistan's biggest city and financial hub.
In June 201,1 the Rangers came under fire when they shot dead a young man in a public park in Clifton initially claiming he was a criminal.
Later, three personnel were charged with murder.