"The US government and army cannot make Pakistan a scapegoat for its failures in Afghanistan," Foreign Office Spokesperson Nafees Zakaria said, the Dawn newspaper reported.
"It is clear to me that the Inter-Services Intelligence (ISI) has connections with terrorist groups," Chairman of the Joint Chiefs of Staff General Joseph Dunford had told the US Senate Armed Services Committee on Tuesday.
Zakaria said Pakistan has cleared its areas and begun a decisive offensive against terrorists on its soil.
The top American general on Tuesday was joined by his Defence Secretary Jim Mattis in slamming the ISI.
"We have seen havens left to the terrorists' own devices. We have seen the government of Pakistan come down on terrorism, while ISI appears to run its own foreign policy," Mattis had said, acknowledging for the first time in public domain that ISI runs its own policy and does not seem to be controlled by the federal government.
"The US is trying to blame Pakistan for its failures in Afghanistan," Zakaria said, according to the report.