The two were executed at the Central Jail of Multan city in the largest province of Punjab.
Officials said that both prisoners were convicted for murders and had exhausted all appeals against the capital punishment.
Pakistan resumed hangings after the deadly Peshawar school attack in December and had executed at least 176 prisoners since then.
The government on June 13 decided the halt executions for a month ahead of Ramzan.
The executions are opposed by the European Union (EU) and the right groups.
Rights groups say many convictions are highly unreliable in Pakistan where criminal justice system barely functions and torture has often been used to extract confessions.
There are some 8,000 convicted prisoners in various jails of the country.