"If confirmed, I will work with the State Department and the Congress to incentivise Pakistan's co-operation on issues critical to our national interests and the region's security, with focus on Pakistan's need to expel or neutralise externally-focused militant groups that operate within its borders," said Gen (retd.) Mattis.
In his written written submission to the Senate Armed Services Committee ahead of his confirmation hearing, Mattis noted that "conditioning our security assistance" to Pakistan has a mixed history, "but I will review all option."
Nick-named as "Mad Dog" Mattis, the retired general told lawmakers that Pakistan has "learned some hard lessons" because of its dealings with the Afghan Taliban, as violence in that country reflects.
"I believe they should do more to collaborate with their neighbor. We should urge Pakistan to take further actions against the Taliban and the Haqqani network," Mattis said.
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Haqqani network, which is linked to al-Qaeda, has been blamed for several deadly attacks against Western and Indian interests in Afghanistan, including the 2008 bombing of the Indian mission in Kabul.
Arguing that countries in the region "have the responsibility to support the reconciliation process" in Afghanistan, Mattis said the countries in the region "should increase pressure on the Afghan Taliban and associated militant networks" to stop their campaigns of violence.
He said US' ties with Pakistan have had highs and lows.
For years, Mattis said, Pakistan has battled internally- focused extremist organizations within its border and with US help.
"In a sign of its commitment, its military has suffered significant casualties in this counterinsurgency effort," he said, adding that the US has conducted military exercises with Pakistan in an effort to increase thrust and interoperability.