"The statement of the Indian Defence Minister should be a matter of concern not just to Pakistan but also others in the region and beyond," Foreign Office spokesperson Qazi Khalillulah said at his weekly briefing.
"Let me say that we will take all appropriate measures that are required to protect our national interest," he said when asked about steps being taken after Parrikar's statement.
"Their statements confirm Pakistan's apprehensions about India's involvement in terrorism in Pakistan," he said.
The spokesperson said that Adviser to the Prime Minister on National Security and Foreign Affairs, Sartaj Aziz, and Defence Minister Khawaja Asif have already responded and Senate's Defence Committee has also condemned the statement of the Indian leader.
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"We have lost more than 60,000 lives of our citizens and suffered economic losses of more than USD 100 billion. Pakistan condemns terrorism in all its forms and manifestations," he said.
To a question about India allegedly working against the Pakistan-China Economic Corridor (CPEC), he said Pakistan is aware of it "including propaganda by Indian media".
"However, I wish to reiterate our commitment to the realisation of Pak-China Economic Corridor projects, which will benefit the entire region," he said.
He said both Pakistan and China were committed to the realisation of these projects.